3-Amino-1-propanesulfonic acid Usage And Synthesis
Chemical Properties
White Powder
Uses
Important gaba mimetic agent. It evokes neurological responses similar to those elicited by g-aminobutyric acid
Biological Activity
Sulfated glycosaminoglycan (sGAG) mimetic that targets soluble amyloid β (A β ) and maintains A β in a non-fibrillar form. Decreases A β 42-induced neuronal death and inhibits amyloid deposition in vitro . Decreases brain amyloid plaque load by 30%, increases tau polymerization and is brain penetrant. Also a GABA analog that protects against the convulsant and cytotoxic activity of kainic acid in vivo .
3-Amino-1-propanesulfonic acid Preparation Products And Raw materials
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