2,4,6-Trimethylbenzoic acid Basic information |
Product Name: |
2,4,6-Trimethylbenzoic acid |
Synonyms: |
TMBA;RARECHEM AL BO 0328;2,4,6-trimethyl-benzoicaci;Benzoicacid,2,4,6-trimethyl-;beta-Isodurylic acid;beta-isodurylicacid;2,4,6-TRIMETHYLBENZOIC ACID;2-MESITYLENECARBOXYLIC ACID |
CAS: |
480-63-7 |
MF: |
C10H12O2 |
MW: |
164.2 |
EINECS: |
207-553-9 |
Product Categories: |
Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts;Organic acids;API intermediates |
Mol File: |
480-63-7.mol |
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2,4,6-Trimethylbenzoic acid Chemical Properties |
Hazard Codes |
Xn |
Risk Statements |
20/21/22 |
Safety Statements |
22-24/25-36 |
WGK Germany |
3 |
RTECS |
DI0887010 |
TSCA |
Yes |
HS Code |
29163900 |
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2,4,6-Trimethylbenzoic acid Usage And Synthesis |
Chemical Properties |
white to almost white crystalline powder |
Definition |
ChEBI: A trimethylbenzoic acid in which the three methyl substituents are located at positions 2, 4 and 6. |
Synthesis Reference(s) |
Journal of the American Chemical Society, 96, p. 590, 1974 DOI: 10.1021/ja00809a049
Organic Syntheses, Coll. Vol. 3, p. 553, 1955
Tetrahedron Letters, 11, p. 4459, 1970 |
Purification Methods |
Crystallise mesitoic acid from water, ligroin or carbon tetrachloride [Ohwada et al. J Am Chem Soc 108 3029 1986]. [Beilstein 9 H 553, 9 I 214, 9 II 360, 9 III 2489, 9 IV 1854.] |
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2,4,6-Trimethylbenzoic acid Preparation Products And Raw materials |
Raw materials |
Methanesulfonic acid, 1,1,1-trifluoro-, 2,4,6-trimethylphenyl ester-->2,4,6-TRIMETHYLBENZENEBORONIC ACID NEO GLYCOL CYCLIC ESTER-->Methyl 2,4,6-trimethylbenzoate-->SodiuM 2,4,6-triMethylbenzenesulfinate-->Mesitylene-->2,4,6-TRIMETHYLPHENYLMAGNESIUM BROMIDE-->Formic acid-->2,4,6-Trimethylbenzyl alcohol-->Trichloroacetyl chloride-->2',4',6'-TRIMETHYLACETOPHENONE-->Mesitaldehyde-->CARBON DIOXIDE |
Preparation Products |
2,4,6-Trimethylbenzoyl chloride-->γ-Hydroxybutyrophenone |
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