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Indole-4-carboxaldehyde Basic information |
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Indole-4-carboxaldehyde Chemical Properties |
Melting point |
139-143 °C(lit.) |
Boiling point |
339.1±15.0 °C(Predicted) |
density |
1.278±0.06 g/cm3(Predicted) |
storage temp. |
Keep Cold |
pka |
15.84±0.30(Predicted) |
Water Solubility |
Soluble in ethanol and . Insoluble in water. |
Sensitive |
Air Sensitive |
CAS DataBase Reference |
1074-86-8(CAS DataBase Reference) |
NIST Chemistry Reference |
1H-indole-4-carboxaldehyde(1074-86-8) |
Hazard Codes |
Xn,Xi |
Risk Statements |
22-36-43 |
Safety Statements |
26-36/37 |
WGK Germany |
3 |
Hazard Note |
Irritant/Keep Cold |
HazardClass |
IRRITANT |
HS Code |
29333990 |
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Indole-4-carboxaldehyde Usage And Synthesis |
Chemical Properties |
White to dark brown solid |
Uses |
Indole-4-carboxaldehyde is usually used as reactant in Biginelli reaction,preparation of antitumor agents,intramolecular Friedel-Crafts acylation,preparation of inhibitors of cell division in E. Coli,synthesis of Hantzsch pyridine-containing Schiff bases. |
Synthesis Reference(s) |
The Journal of Organic Chemistry, 46, p. 1752, 1981 DOI: 10.1021/jo00321a053
Tetrahedron, 39, p. 3695, 1983 DOI: 10.1016/S0040-4020(01)88608-7 |
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Indole-4-carboxaldehyde Preparation Products And Raw materials |
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