China Largest Manufacturer Factory Supply Argireline (Acetyl Hexapeptide-8) CAS 616204-22-9 for cosmetic use
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Purity99.9%
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UseCosmetics
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OriginChina
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Package1g/10g/100g/1000g/package
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ManufacturerXI'AN LEADER BIOCHEMICAL ENGINEERING CO.,LTD
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Place of OriginCHINA
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Brand Nameinfo@leader-biogroup.com
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CertificationISO,GMP,SGS,HALA,KOSER,HACCP
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Model NumberAAAAA
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Minimum Order Quantity1g
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PriceNegotiate Depend on order quantity
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Packaging Details100g/package
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Delivery Time2-3 working days
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Payment TermsWestern Union, MoneyGram, T/T, L/C
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Supply Ability20kgs/month
China Largest Manufacturer Factory Supply Argireline (Acetyl Hexapeptide-8) CAS 616204-22-9 for cosmetic use
China Largest Manufacturer Factory Supply Argireline (Acetyl Hexapeptide-8) CAS 616204-22-9 for cosmetic use
Inquiry email: info@leader-biogroup.com
Hot Line +86-029-68895030
ACETYL HEXAPEPTIDE-8
| CAS Number | 616204-22-9 |
| Chem/IUPAC Name: | Acetyl hexapeptide-8 is the synthetic peptide consisting of arginine, methionine, and acetylated glutamic acid residues |
| COSING REF No: | 54135 |
Acetyl Hexapeptide-8, commonly known as Argireline, is a peptide used in cosmetics for its potential anti-aging effects. It is a synthetic peptide made up of six amino acids. Acetyl Hexapeptide-8 is believed to work by reducing the appearance of fine lines and wrinkles caused by facial expressions. It is often found in skincare products, particularly those targeting the signs of aging. In terms of appearance, Acetyl Hexapeptide-8 is typically a white, crystalline powder. Consumers can find a range of skincare products formulated with Acetyl Hexapeptide-8, such as serums, creams, and anti-aging treatments. The chemical formula of Acetyl Hexapeptide-8 is C34H60N14O12S.
What is ACETYL HEXAPEPTIDE-8 used for?
Acetyl Hexapeptide-8 is used widely in cosmetics and personal care products for its potential anti-aging properties. It is primarily employed as a topical alternative to Botox, aiming to reduce the appearance of fine lines and wrinkles caused by facial muscle contractions. Acetyl Hexapeptide-8 works by inhibiting the release of neurotransmitters that stimulate muscle contractions, resulting in a temporary relaxation of facial muscles. This peptide is often incorporated into skincare formulations, including serums and creams, targeting specific areas prone to wrinkles, such as the forehead, crow's feet, and frown lines.
Origin
Acetyl Hexapeptide-8 is produced through synthetic methods using solid-phase peptide synthesis. The process involves sequentially coupling and activating the amino acids to form the hexapeptide chain. Acetyl groups are added to the N-terminus of the peptide to enhance stability and efficacy.
What does ACETYL HEXAPEPTIDE-8 do in a formulation?
- Humectant
- Skin conditioning
Safety profile
Acetyl Hexapeptide-8 is a non-toxic ingredient and is safe for the skin. It is also not known to be comedogenic, meaning it does not cause acne and breakouts. Nevertheless, patch testing should be done before using any product containing Acetyl Hexapeptide-8. Lastly, being synthetically derived, this ingredient is vegan and does not have any animal based components.
| Argireline Basic information |
| Product Name: | Argireline |
| Synonyms: | Ac-Glu-Glu-Met-Glu-Arg-Arg-NH2;N-Acetyl-L-alpha-glutamyl-L-alpha-glutamyl-L-methionyl-L-glutaminyl-L-arginyl-L-argininamide;Acetyl Hexapeptide-3/Acetyl Hexapeptide-8;Argireline,Acetyl hexapeptide-3, BR;Anti-Wrinkle Multi-Peptides;Reproage;Argireline;Argireline acetate Ac-Glu-Glu-Met-Arg-Arg-NH2 |
| CAS: | 616204-22-9 |
| MF: | C34H60N14O12S |
| MW: | 889 |
| EINECS: | 1592732-453-0 |
| Product Categories: | 616204-22-9 |
| Mol File: | 616204-22-9.mol |
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| Argireline Chemical Properties |
| density | 1.54 |
| storage temp. | -20°C |
| solubility | water soluble |
| solubility | water soluble |
| form | lyophilized solid |
| pka | 4.43±0.10(Predicted) |
| color | white |
| Sequence | Ac-Glu-Glu-Met-Gln-Arg-Arg-NH2 |
| InChIKey | RJZNPROJTJSYLC-LLINQDLYSA-N |
| Safety Information |
| WGK Germany | 2 |
| Argireline Usage And Synthesis |
| Description |
Argireline is made up of chains of amino acids. Such chains can affect how our cells work, e.g. relaxing our face muscles. It is derived from the peptide Acetyl hexapeptide-3, a substrate of Botulinum toxin, or more commonly known as Botox. |
| Application |
Botox is a common, anti-wrinkle treatment which is applied using a needle. You may achieve the same anti-aging results with products which contain Argireline. Argireline can help prevent the formation of wrinkles by inhibiting muscle movement in the face. Because of this, Argireline cream is sometimes known as “Botox in a jar.” |
| Uses | Argireline is an anti-wrinkle peptide. Synthetically produced and considered to be highly effective, clinical studies indicate it can reduce the depth of existing wrinkles. May be incorporated into products marketed as having a topical-BoToX. or “wrinkle-erasing” effect. |
| benefits | Acetyl Hexapeptide-8 is effectivly reduce various kind of facial wrinkles;Replenish the collagen and polysaccharide, repairthe skin.Winkey patented productin China.It is recommended dosage is 3~10%. |
| Clinical claims and research | Argireline is a synthetic oligopeptide that emulates the sequence of SNAP-25, a type of SNARE. It has significant skin permeation, interferes with the SNARE ternary complex, and has demonstrated interference with catecholamine release from chromaffin cells. Topical use of 10% argireline resulted in a reduced depth and roughness of periorbital wrinkles in 10 healthy women. One study on 14 volunteers showed that 5% argireline reduced periorbital wrinkles by 32% in 28 days. Most recently, argireline’s efficacy has been measured in 60 Chinese women from a randomized control trial. Its total efficacy was 48.9% compared to 0% in the placebo group, and resulted in significantly decreased wrinkle roughness. |
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