| Calcium 2-oxoglutarate Basic information |
| Product Name: |
Calcium 2-oxoglutarate |
| Synonyms: |
ALPHA-KETOGLUTARATE CALCIUM MONOHYDRATE;A-KETOGLUTARIC ACID, CALCIUM SALT, MONOHYDRATE;Calcium 2-oxoglutarate;Pentanedioic Acid ,2-oxo-,Calcium Salt;α-Ketoglutaric acid calcium salt;2-Oxopentanedioic acid calcium salt;Calcium 2-oxopentanedioate;Ca-ketoglutarate |
| CAS: |
71686-01-6 |
| MF: |
C5H8CaO5 |
| MW: |
188.19 |
| EINECS: |
275-843-2 |
| Product Categories: |
|
| Mol File: |
71686-01-6.mol |
 |
| |
| Calcium 2-oxoglutarate Chemical Properties |
| Melting point |
>300°C (not melting) |
| storage temp. |
-20°C, Hygroscopic |
| solubility |
Aqueous Acid (Slightly), Water (Slightly, Heated, Sonicated) |
| form |
Solid |
| color |
White to Off-White |
| Water Solubility |
Water: Insoluble |
| Stability: |
Hygroscopic |
| InChI |
InChI=1S/C5H6O5.Ca.2H/c6-3(5(9)10)1-2-4(7)8;;;/h1-2H2,(H,7,8)(H,9,10);;; |
| InChIKey |
YWFUOMFSJDJVPT-UHFFFAOYSA-N |
| SMILES |
C(=O)(C(=O)O)CCC(=O)O.[Ca] |
| CAS DataBase Reference |
71686-01-6(CAS DataBase Reference) |
| |
| Calcium 2-oxoglutarate Usage And Synthesis |
| Description |
Calcium 2-oxoglutarate is a reversible tyrosinase inhibitor, an intermediate in the production of ATP or GTP in the Krebs cycle, and a major carbon skeleton for nitrogen assimilation reactions. It has a variety of biological roles and can be used as a precursor for the synthesis of glutamate, an enzyme involved in the synthesis of amino acids and fatty acids, involved in the transcriptional regulation of cells and influencing plant metabolism, among other roles. Recent studies have demonstrated that mitochondria-mediated calcium 2-oxoglutarate in the rat heart is capable of controlling the formation of aspartic acid. |
| Uses |
Calcium 2-Oxoglutarate helps stabilie redox homeostasis and helps improve arterial elasticity. |
| Application |
Calcium 2-oxoglutarate is the Calcium salt form of 2-oxoglutarate. 2-oxoglutarate is naturally found in organisms and is a well-known intermediate in the production of ATP or GTP in the Krebs cycle. |
| Biological Activity |
Calcium 2-oxoglutarate is an intermediate in the production of ATP or GTP in the Krebs cycle. It also acts as the major carbon skeleton for nitrogen-assimilatory reactions. Calcium 2-oxoglutarate is a reversible inhibitor of tyrosinase (IC50=15 mM). |
|
|
