China Original Factory Manufacturer Supply High Quality Alpha Ketoglutaric Acid(AKG)/2-Ketoglutaric Acid CAS 328-50-7

2-Ketoglutaric acid Basic information

ALPHA-KETOGLUTARATE

A-cétoglutarate, A-Ketoglutaric Acid, Acide 2-Oxoglutarique, Acide a-cétoglutarique, Acide Alpha-Cétoglutarique, Alfa-Cetoglutarato, Alpha-Cétoglutarate, Alpha-Cétoglutarate d'Arginine, Alpha-Cétoglutarate de Calcium, Alpha-Cétoglutarate de Créatine, Alpha-Cétoglutarate de Glutamine, Alpha-Cétoglutarate de L-Arginine, Alpha-Cétoglutarate de L-Leucine, Alpha-Cétoglutarate de Taurine, Alpha Keto Glutaric Acid, Alpha Ketoglutarate, Alpha Ketoglutaric Acid, Alpha KG, AAKG, AKG, Arginine Alpha-Ketoglutarate, Calcium Alpha-Ketoglutarate, Creatine Alpha-Ketoglutarate, Glutamine Alpha-Ketoglutarate, L-Arginine AKG, L-Arginine Alpha Keto Glutarate, L-Leucine Alpha-Ketoglutarate, Taurine Alpha-Ketoglutarate, 2-Oxoglutaric Acid, 2-Oxopentanedoicic Acid

Product Name:	2-Ketoglutaric acid
Synonyms:	2-KETOGLUTARIC ACID;2-OXOGLUTARIC ACID;2-OXOPENTANEDIOIC ACID;A-KETOGLUTARIC ACID;Glutaric acid, 2-oxo-;Glutaric acid, alpha keto;-Ketoglutaricacid;α-Ketoglutaricacid
CAS:	328-50-7
MF:	C5H6O5
MW:	146.1
EINECS:	206-330-3
Product Categories:	Nutrition;food additives;Pharmaceutical Intermediates;Aliphatics;Organic acids;pharm raw material;Amino Acids;Food Additives;bc0001;328-50-7
Mol File:	328-50-7.mol

2-Ketoglutaric acid Chemical Properties

Melting point	113-115 °C
Boiling point	185.67°C (rough estimate)
density	1.2821 (rough estimate)
vapor pressure	0.01Pa at 25℃
refractive index	1.3920 (estimate)
FEMA	3891 \| 2-OXOPENTANEDIOIC ACID
storage temp.	2-8°C
solubility	H2O: soluble0.1g/mL, clear, colorless
form	Crystalline Powder
pka	2.47(at 25℃)
color	White to slightly yellow
Odor	Odorless
PH	3.09(1 mM solution);2.36(10 mM solution);1.77(100 mM solution)
Water Solubility	Soluble in water, methanol and dimethyl sulfoxide.
Merck	14,5303
JECFA Number	634
BRN	1705689
InChIKey	KPGXRSRHYNQIFN-UHFFFAOYSA-N
LogP	-2.08 at 25℃
CAS DataBase Reference	328-50-7(CAS DataBase Reference)
NIST Chemistry Reference	2-Oxopentanedioic acid(328-50-7)
EPA Substance Registry System	Pentanedioic acid, 2-oxo- (328-50-7)

Safety Information

Hazard Codes	Xi,T
Risk Statements	37/38-41-36/37/38-23/24/25
Safety Statements	26-39-45-36/37/39
WGK Germany	3
TSCA	Yes
HS Code	29183000

MSDS Information

Provider	Language
alpha-Ketoglutaric acid	English
SigmaAldrich	English
ACROS	English
ALFA	English

2-Ketoglutaric acid Usage And Synthesis

Description

2-Ketoglutaric acid also known as α-Ketoglutaric acid (AKG) is a chemical found in the body. It is a ketone derivative of the organic compound glutaric acid. It is important for the proper metabolism of all essential amino acids and the transfer of cellular energy in the citric acid or Krebs cycle. In combination with L-glutamate, AKG can reduce levels of ammonia formed in the brain, muscles, and kidneys, as well as help balance the body’s nitrogen chemistry and prevent nitrogen excess in body tissues and fluids.
α-Ketoglutaric acid is used for kidney disease; intestinal and stomach disorders, including bacterial infections; liver problems; cataracts; and recurring yeast infections. It is also used for improving the way kidney patients receiving hemodialysis treatments process protein.