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beta-Sitosterol Basic information |
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beta-Sitosterol Chemical Properties |
Melting point |
136-140 °C(lit.) |
alpha |
-28 º (c=2, CHCl3) |
Boiling point |
473.52°C (rough estimate) |
density |
0.9540 (rough estimate) |
refractive index |
1.5000 (estimate) |
storage temp. |
−20°C |
solubility |
chloroform: 20 mg/mL, clear, colorless |
pka |
15.03±0.70(Predicted) |
form |
White solid |
Water Solubility |
INSOLUBLE |
Merck |
14,8556 |
BRN |
1916165 |
InChIKey |
KZJWDPNRJALLNS-VJSFXXLFSA-N |
CAS DataBase Reference |
83-46-5(CAS DataBase Reference) |
NIST Chemistry Reference |
«beta»-Sitosterol(83-46-5) |
EPA Substance Registry System |
.beta.-Sitosterol (83-46-5) |
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beta-Sitosterol Usage And Synthesis |
Chemical Properties |
White powder |
Uses |
A common sterol in plants. Isolated from wheat germ oil, corn oil. Antilipemic. Used in the treatment of prostatic adenoma. |
Uses |
antiinflammatory, immunomodulator |
Definition |
ChEBI: A phytosterols that is stigmast-5-ene substituted by a beta-hydroxy group at position 3. |
Definition |
A with long aliphatic side chains (8–10 carbons) and at least one hydroxyl group. They are lipidsoluble and often occur in membranes. Examples are cholesterol and ergosterol. |
Definition |
sterol: Any of a group of basedalcohols having a hydrocarbonside-chain of 8–10 carbon atoms.Sterols exist either as free sterols oras esters of fatty acids. Animal sterols(zoosterols) include cholesterol andlanosterol. The major plant sterol(phytosterol) is beta-sitosterol, whilefungal sterols (mycosterols) includeergosterol. |
Purification Methods |
Crystallise -sitosterol from EtOH, MeOH, Me2CO, Me2CO/EtOH or Me2CO/MeOH. It has also been purified by zone melting. The acetate crystallises from MeOH or EtOH as plates with m 127128o and [] D 20 -41o (c 2, CHCl3). The benzoate crystallises from EtOH as needles with m 146-147o and [] D 20 –13.8o (c 2, CHCl3). [Fujimoto & Jacobson J Org Chem 29 3377, 3381 1964, Shoppee J Chem Soc 10431948, Heilbron et al. J Chem Soc 344, 347 1941, Beilstein 6 III 2696.] |
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beta-Sitosterol Preparation Products And Raw materials |
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